Linear and whorled nevoid hypermelanosis with hyper IgE syndrome

Linear and whorled nevoid hypermelanosis with hemiatrophy.

FIG. 1 Linear and Whorled Nevoid Hypermelanosis: Linear and whorled hyperpigmented macules in a reticulate pattern along the Blaschko’s lines over trunk and limbs. A two-years-old boy presented with abnormal body pigmentation and body asymmetry noted since birth. A preceding vesicular eruption was absent. He was developmentally normal. Family history was insignificant. Examination revealed line...

Linear and whorled nevoid hypermelanosis in three successive generations.

Sir, Linear and whorled nevoid hypermelanosis (LWNH) is characterized by hyperpigmented macules in a streaky configuration along the lines of Blaschko, without preceding inflammation or atrophy.[1-3] Lesions are distributed mainly on the trunk and extremities, sparing palms, soles, and mucosae. The usual age of the onset of hyperpigmentation occurs within the first few weeks of life, continues ...

Linear and whorled nevoid hypermelanosis and Axenfeld-Rieger anomaly: a novel association.

معرفی یک مورد سندرم ازدیاد Hyper-IgE Syndrome) IgE)

Hyper IgE syndrome (Job’s syndrome) is a primary immunodeficiency disease with recurrent infections especially staphylococcal, coarse face, skeletal abnormality and significant increase in serum IgE level (IgE >2000IU/ml). We present a 16 years old boy admitted with chronic cough, dyspnea, eczema and pneumatocele. He had a history of chronic dermal infection since 1 month after birth. The dia...

Hyper-IgE syndrome